Megaloblastic Anaemia Associated with Anticonvulsant Therapy
نویسندگان
چکیده
منابع مشابه
Megaloblastic anaemia associated with anticonvulsant therapy.
In 1954 Badenoch described two cases of megaloblastic anaemia which developed in epileptics while under treatment with phenytoin sodium and phenobarbitone, and subsequently I2 further cases have been recorded (Hawkins and Meynell, 1954; Chalmers and Boheimer, I954; Rhind and Varadi, I954; Webster, 1954; Berlyne, Levene and McGlashan, 1955; Ryan and Forshaw, I955; Vaishnava, I955). Six of these ...
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Two cases of anticonvulsant megaloblastic anaemia are described, showing features of unusual interest. Though both cases were apparently deficient in folic acid, the Figlu tests were negative. One patient had an extremely low serum B(12) concentration apparently associated with defective B(12) absorption due to deficiency of intrinsic factor, and both showed impaired intestinal absorption of D-...
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Nowadays scurvy is fortunately rare. Cases are still found among the inmates of common lodging houses and those living alone, where age, decrepitude, or apathy may have led to an inadequate dietary intake. Rigid dieting as in peptic ulcer' may be an unusual cause. While the blood picture may show little change in the milder cases, anaemia of variable degree occurs in most adults with scurvy. It...
متن کاملRare case with megaloblastic anaemia.
A nine years old boy presented with history of pallor and anaemia since early infancy along with neural hearing loss responding to empirical multivitamin and folic acid therapy started on basis of blood complete picture showing anaemia and megaloblastic anaemia. On investigation he was diagnosed with Thiamine Responsive Megaloblastic Anaemia, a very rare condition in our settings.
متن کاملPigmentation in megaloblastic anaemia associated with pregnancy and lactation.
Generalized skin pigmentation in five African women with megaloblastic anaemia in the postnatal period was associated with low serum folate levels, as distinct from vitamin B(12) deficiency. It is suggested that the occurrence of pigmentation in both folate and vitamin B(12) deficiency may reflect a common abnormality of metabolism.
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ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 1957
ISSN: 0032-5473
DOI: 10.1136/pgmj.33.379.242